Brian

Correlation Found Between Thai Kratom Users and “Good” Cholesterol Levels

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A new study from Thailand (La-up, 2021) found traditional users of kratom had elevated levels of high-density lipoprotein (HDL or “good” cholesterol) and low levels of triglycerides, or “fats from the food we eat that are carried in the blood” (Cleveland Clinic 2019). High HDL, low levels of low-density lipoprotein (LDL or “bad” cholesterol), and …

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Kratom Under a Microscope

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A group of scientists from the Malaysian Agricultural Research and Development Institute have documented the anatomy of the kratom plant. In the study published Tropical Life Sciences Research, scientists documented not only the anatomy, but the “micromorphology characteristics” of kratom plants collected from Malaysia. The study provided botanical evidence kratom is indeed a species of …

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Happy 4/20! Every American should have the right to grow plant medicine

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Every American should have the right to grow their own plant medicine in their backyard, greenhouse, or inside their residence. Plants including kratom, poppies, cannabis, and psilocybin mushrooms should be just as legal to grow as coffee, sunflowers, tomatoes, and shiitakes. The right to have a plant medicine garden could be protected just as the …

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List of “New” Psychoactive Substances of Natural Origin

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Note: This article is a summary of the journal article cited as follows:Gonçalves, J., Luís, Â., Gallardo, E., & Duarte, A. P. (2021). Psychoactive Substances of Natural Origin: Toxicological Aspects, Therapeutic Properties and Analysis in Biological Samples. Molecules (Basel, Switzerland), 26(5), 1397. https://doi.org/10.3390/molecules26051397Full text: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7961374/ Scientists from Portugal, where the possession and consumption of all …

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Teenager Attempts Suicide by Swallowing 45 Kratom Capsules

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In a 2020 case report, a teenage girl intentionally overdosed on 45 kratom capsules (500mg each = 22.5 grams or 4/5 ounce). After suffering from severe depression, the 15 year old obtained the capsules from her father, and swallowed them in an attempted suicide. On exam, patient complained of dry mouth, dizziness, restlessness, palpitations, nausea, …

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Inteview with Pharmacokineticist and Kratom Researcher Dr. Abhisheak Sharma

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For audio of this interview as well as studies cited here see Kratom Science Podcast #45 KratomScience: You have your background in pharmacokinetics. What made you interested in going into that field? Dr. Abhisheak Sharma: So basically I did my PhD in 2015 and I moved to the States to do my post-doctoral studies with …

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Study: 7-hydroxymitragynine Metabolizes into the More Potent ‘Mitragynine Pseudoindoxyl’ in Human Plasma

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A study out of University of Florida published in the journal ACS Pharmacology & Translational Science found that the potency of powder kratom may be due not only to the increased level of 7-hydroxymitragynine (7-HMG), but the way the 7-HMG metabolizes in human plasma (Kamble 2020). Fresh kratom consumed traditionally in Southeast Asia has been …

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Levels of Kratom Alkaloid Mitragynine Were Likely Overestimated in Autopsies

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A research article in the journal Drug Testing and Analysis uncovered a flaw in previous examinations of kratom’s main alkaloid, mitragynine. The study, lead by University of Florida pharmacutics researcher Dr. Abisheak Sharma, stated: There is a possibility that earlier reported studies did not separate the four mitragynine diastereomers, resulting in over‐quantification of mitragynine in …

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