Herb-induced liver injury (HILI) is “a rare adverse reaction associated with the consumption of herbal products”. A review published in 2020 found 12,068 cases of herb-induced liver injury worldwide, as well as 46,266 cases of liver injury induced by the use of drugs (Teschke et al., 2021). Herbal and dietary supplements contribute to 20% of …
Possible causes of kratom-related liver toxicities and deaths Read More »
This interview is a transcript of Kratom Science Podcast #69 Kratom Science: I want to start off with Dr. McCurdy. You were originally with University of Mississippi. That university is known for the only federally legal cannabis farm. You started to study kratom around 2004, and I’m just wondering how you became interested in kratom? …
On May 2nd, the Pennsylvania House Democratic Policy Committee @PADemPolicy posted on Twitter that it was “in Allentown with @RepSchlossberg for a roundtable on the Evolving Epidemic: Opioids and Treatment Options.” Then in a reply to this tweet, wrote “Kratom is widely available but suppresses breathing much the same way as heroin.” As anyone who …
Pennsylvania House Democrats Compare Kratom to Heroin in Pseudoscientific Tweet Read More »
In a new study by the team at University of Florida, scientists found that the metabolite 7-hydroxymitragynine does not account for the pain-relieving effects of its parent alkaloid, mitragynine (Berthold et al., 2021). Here we investigated the hotplate antinociception, pharmacokinetics, and tissue distribution of mitragynine and 7-hydroxymitragynine at equianalgesic oral doses in…mice to determine the …
A recent review of the National Survey on Drug Use and Health (NSDUH) found adolescents reported use of kratom in very low numbers. Less than one half of one percent, only 0.44%, of respondents age 12-17 reported ever having used kratom in their lives. Only 0.27% said they consumed kratom in the past month (Sharma …
Dr. Fabian Pitter Steinmetz is a toxicologist from Germany who in 2021 testified for the World Health Organization’s (WHO) 44th Expert Committee on Drug Dependence (ECDD). There, Dr. Steinmetz gave the case for why kratom should be kept legal. As a member for the European Coalition for Just and Effective Drug Policies (ENCOD), he is …
Coffee is a tropical evergreen plant originating in Ethiopia but now grown worldwide. Two species, Coffea arabica and Coffea canephora, are predominantly sold as a recreational stimulant. Referred to “joe”, “java”, “brew”, “mud”, “liquid cocaine”, “espresso” and “go juice”, coffee is a drug of abuse, primarily used for its psychoactive and stimulant effects, similar to …
Dr. Lance McMahon is Chair of the Department of Pharmacodynamics at University of Florida College of Pharmacy. Dr. McMahon is involved in pioneering kratom research that looks at the various kratom alkaloids, how they function on our brain receptors, and how that creates kratom’s complex effects on our bio. We talk about this research, where …
A pharmacologist today may regard traditional and plant medicine as primitive, and may entirely disregard thousands of years of use and thousands of modern-day testimonies of positive outcomes because it has not been through the rigors of hard science. On the other hand, the massive spread of anti-science misinformation has cast sometimes unreasonable doubt on …
Combining traditional plant medicine with modern medical technology Read More »
In October 2018 we covered a sensationalist news story out of Florida where the director of a for-profit rehabilitation center claimed that kratom caused hallucinations (Scripps Media, 2018). Multiple news stories, press releases by government agencies, and even peer-reviewed published studies have made this claim, all without a shred of hard evidence. The most comprehensive …
A list of baseless claims that kratom causes hallucinations Read More »