This is the Kratom Science Journal Club with Dr. Jonathan Cachat, neuroscientist and expert in psychopharmacology. In each episode we discuss an article in a peer reviewed journal.
For episode 2 we discuss the article, “The Potential for Kratom as an Antidepressant and Antipsychotic” published in Yale Journal of Biology and Medicine, edition 93, June 2020 and co-authored by Kratom Science Podcast guest Marc Swogger.
How do dopamine, serotonin, and cortisol work to affect psychosis and depression? What effect does mitragynine have on our brains? How is mitragynine metabolized? How does kratom work differently from opiates and psychedelics? And finally why were these substances made illegal, rendering these questions tough to answer even in the 21st century?
Full citation of article discussed: Johnson LE, Balyan L, Magdalany A, et al. The Potential for Kratom as an Antidepressant and Antipsychotic. Yale J Biol Med. 2020;93(2):283-289. Published 2020 Jun 29.
Dr. Cachat’s website http://jcachat.com/
Music: “Moonrunner” by Captain Bigwheel
Produced by Brian Gallagher for KratomScience.com
Disclaimer: There is no content on the Kratom Science Podcast nor on KratomScience.com that in any way constitutes medical claims or medical advice. You should consult a medical professional for medical advice and we believe this sincerely. Take care.
I read a book called “Chasing the Scream”
Johann Hari. http://www.chasingthescream.com/wp-content/uploads/2014/09/chasing-the-scream-3.png
The opioid dilemma did not start in the 2000s in 1990 and 1980 in 1970’s. It started in the early 1900s I believe. Please read this book a true history from an investigative reporter.
This young generation thinks it started with them and the fentanyl I know people that were heroin addicts in the 50s not with us anymore, of course. I won’t tell you why she saying the screen is the name of the book or I’ll ruin the whole book for you
I am a recovering alcoholic and I was a heroin user for years back in the 70s. So I was very interested in the history. Thanks for listening
Thanks for your comment Lisa. I’m currently reading that book!
About 8 months ago I started a kratom regiment aimed at my diagnosed clinical depression. I have refused pharmaceuticals because I don’t like the side effects and I have had great success with kratom. It’s not dialed in to perfection yet but it’s far better than I was taking nothing.