For #29 of Kratom Science Journal Club, JC and Brian look at a 2019 report on toxicological events having to do with mitragynine. Does mitragynine increase the effects of other drugs? How toxic is kratom on its own? Other alkaloids have commonly been counted as mitragynine, so what are the ramifications? All this and other “medicolegal” issues.
Plus, we talk about the Cannabis Museum in Athens Ohio. When will it open? Probably not on 4/20, but close enough.
References
- Papsun, D. M., Chan-Hosokawa, A., Friederich, L., Brower, J., Graf, K., & Logan, B. (2019). The Trouble With Kratom: Analytical and Interpretative Issues Involving Mitragynine. Journal of analytical toxicology, 43(8), 615–629. https://doi.org/10.1093/jat/bkz064
- Takayama H. (2004). Chemistry and pharmacology of analgesic indole alkaloids from the rubiaceous plant, Mitragyna speciosa. Chemical & pharmaceutical bulletin, 52(8), 916–928. https://doi.org/10.1248/cpb.52.916
- Quote from Dr. Abhisheak Sharma from Episode #45 of the Kratom Science Podcast https://www.kratomscience.com/podcast/45-dr-abisheak-sharma-pharmacokineticist-and-kratom-researcher/
Dr. Jonathan Cachat is on social media @jcachat and http://jcachat.com/
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Music: Captain Bigwheel “Moonrunner”
Kratom Science Journal Club is produced by Brian Gallagher for KratomScience.com
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