Just me this time around. I talk about a soon-to-be-released document I’ve been working on through COVID that’s 200 pages of kratom testimonials from over 800 consumers who posted to KratomScience.com. I talk about a study on kratom and metabolism I blogged about here https://www.kratomscience.com/2020/09/22/study-shows-mitragynine-metabolizes-into-7-hydroxomitragynine/. And I talk about my own history of drinking alcohol …
Citation Kruegel AC, Uprety R, Grinnell SG, et al. 7-Hydroxymitragynine Is an Active Metabolite of Mitragynine and a Key Mediator of Its Analgesic Effects. ACS Cent Sci. 2019;5(6):992-1001. doi:10.1021/acscentsci.9b00141 Summary by KratomScience A study published in 2019 in the open access journal ACS Central Science found what may be a game changer in the pharmacology …
Study shows mitragynine metabolizes into 7-Hydroxymitragynine Read More »
Dr. Cachat and I talk about a study that tested rats with morphine, mitragynine, naloxone, buprenorphine, and rimonabant, and measured responses based on food-reinforcement training. The study concluded “The findings suggest that MG does not induce physiological dependence but can alleviate the physical symptoms associated with morphine withdrawal”. We talk about how the rats are …
Julie Current is a survivor. She had a rough childhood and as an adult she survived physical abuse that led to multiple disabilities like PTSD, chronic pain, and epilepsy. With kratom, kava, and cannabis as tools, she’s coming up on two years sober on October 28. This is Julie Current and this is her kratom …
36. Surviving Abuse and Addiction with Julie Current Read More »
Article Citation with Link to Full Text Harun N, Johari IS, Mansor SM, Shoaib M. Assessing physiological dependence and withdrawal potential of mitragynine using schedule-controlled behaviour in rats. Psychopharmacology (Berl). 2020;237(3):855-867. doi:10.1007/s00213-019-05418-6 Summary by KratomScience Rats were studied in two separate experiments: Experiment 1: Observing withdrawal in rats given morphine vs. rats given mitragynine Three …
Working in a competitive environment in the sales and marketing field, my guest Michael McCunney uses kratom as a stimulant, cognitive boost, and for general well-being. We talk about the importance of doing research, finding a good source, discovering your dose, and staying hydrated. Music: Risey, “Memories of Thailand” The Kratom Science Podcast is produced …
35. Kratom in the Workplace with Michael McCunney Read More »
This episode, Dr. Jon and I use the journal article “Following the Roots of Kratom” published in 2015 by BioMed Research International as a jumping off point to talk about kratom history, human evolution and psychoactive plants, Terence McKenna’s “Stoned Ape” theory, and drug in religious cults . Plus, we answer listener mail about kratom …
Rod the Steelerworker is from Michigan and has been a steelworker for 24 years. As a young man his hobbies were skateboarding and 4-wheeling. As a result of those hobbies, a career doing repetitive physical labor, along with Degenerative Disk Disease, diverticulitis, and IBS, he suffers from chronic pain. A prescription to Norco led him …
34. Rod The Steelworker Switches to Kratom From Norco for Chronic Pain Read More »
Dr. Jon Cachat and I talk about the article “Kratom instrumentalization for severe pain self-treatment resulting in addiction – A case report of acute and chronic subjective effects” – This is an open access article that you can read for free https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7378692/ Müller, E., Hillemacher, T., & Müller, C. P. (2020). Kratom instrumentalization for severe …
This is the Kratom Science Journal Club with Dr. Jonathan Cachat, neuroscientist and expert in psychopharmacology. In each episode we discuss an article in a peer reviewed journal. For episode 2 we discuss the article, “The Potential for Kratom as an Antidepressant and Antipsychotic” published in Yale Journal of Biology and Medicine, edition 93, June …
