medicine

107. Dr. Peter Grinspoon on Cannabis Science and the Drug War

Kratom Science Podcast
Kratom Science Podcast
107. Dr. Peter Grinspoon on Cannabis Science and the Drug War
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Dr. Peter Grinspoon is an instructor at Harvard Medical School, primary care physician at Massachusetts General Hospital, and a 25-year cannabis specialist. His new book, released on 4/20/23 is called Seeing Through the Smoke: A Cannabis Specialist Untangles the Truth About Marijuana. We speak about how the science of cannabis, as well as kratom, is …

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69. Dr. Christopher McCurdy and Dr. Brian Pearson on the Future of Kratom

Kratom Science Podcast
Kratom Science Podcast
69. Dr. Christopher McCurdy and Dr. Brian Pearson on the Future of Kratom
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Dr. Chris McCurdy is a medicinal chemist who has done groundbreaking research on kratom since 2004, starting at the University of Mississippi. In 2017 Dr. McCurdy moved to the University of Florida College of Pharmacy where he continues his research today with an expert team of pharmacologists, unlocking the function of kratom’s many alkaloids and …

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Study: Mitragynine does not rely on its metabolism into 7-hydroxymitragynine to produce pain relieving effects

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In a new study by the team at University of Florida, scientists found that the metabolite 7-hydroxymitragynine does not account for the pain-relieving effects of its parent alkaloid, mitragynine (Berthold et al., 2021). Here we investigated the hotplate antinociception, pharmacokinetics, and tissue distribution of mitragynine and 7-hydroxymitragynine at equianalgesic oral doses in…mice to determine the …

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Journal Club #27: Does Kratom Kill…E-coli and Streptococcus Pneumoniae?

Journal Club with Dr. Jonathan Cachat
Journal Club with Dr. Jonathan Cachat
Journal Club #27: Does Kratom Kill...E-coli and Streptococcus Pneumoniae?
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Spoiler alert: kinda, but its more the quercetin in kratom, which is available in many food plants and as a dietary supplement on its own. This study comes to us from a team at Universitas Nahdlatul Ulama Surabaya (UNUSA) in Surabaya, Indonesia, on the island of Java, south of the island of Kalimantan, where most …

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Journal Club #24: Kratom-Induced Psychosis? A Case Report

Journal Club with Dr. Jonathan Cachat
Journal Club with Dr. Jonathan Cachat
Journal Club #24: Kratom-Induced Psychosis? A Case Report
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Dr. Jonathan Cachat and host Brian Gallagher look at a case report of a supposed kratom-induced psychosis out of a student team from West Virginia University School of Medicine Department of Psychiatry, advised by MDs Alexander Muacevic and John R Adler. A 43 year old man combat veteran with six tours of duty, traumatic brain …

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Cleveland Clinic uses O-desmethyltramadol overdoses to support its claim that “kratom has even caused death”

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Cleveland Clinic is one of the highest ranking and most reputable hospital systems in the United States. The nonprofit established in 1921 (Happy Anniversary!) serves over 7 million patients per year, houses the top cardiology program in the nation, and has international campuses in Canada, the UK, and the United Arab Emirates. The Cleveland Clinic …

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44. Biomedical Educator and Research Scientist Dr. Walter Prozialeck

Kratom Science Podcast
Kratom Science Podcast
44. Biomedical Educator and Research Scientist Dr. Walter Prozialeck
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My guest is Dr. Walter Prozialeck. Originally from Johnstown, PA, Dr. Prozialeck is a biomedical educator and researcher at Midwestern University in Chicago, where he served as chair of the Department of Pharmacology from 1997 to 2018. He’s been studying kratom since 2012. We talk about one of the first research reviews published on kratom …

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Is Kratom a Drug?

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Is kratom a drug, a medicinal herb, a dietary supplement, a “safe food”, a tea? These terms have a whole lot to do with social perception, a little to do with legal issues, and nothing to do with science. Kratom is a shrub that grows natively in Southeast Asia. Botanically, kratom comes from the Rubiaceae …

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23. Social Scientist and Psychologist, Dr. Marc Swogger

Kratom Science Podcast
Kratom Science Podcast
23. Social Scientist and Psychologist, Dr. Marc Swogger
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My guest is Dr. Marc Swogger from the University of Rochester Medical Center, Department of Psychiatry. Dr. Swogger is a social scientist and psychologist who studies substance use. He has co-authored multiple studies on the individual and public health effects of the use of kratom.  Studies discussed in this interview: Marc T. Swogger, Elaine Hart, …

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