pain management

70. Shawn Wenzel on Living with Degenerative Disk Disease

Kratom Science Podcast
Kratom Science Podcast
70. Shawn Wenzel on Living with Degenerative Disk Disease
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My guest from Denver Colorado was diagnosed with degenerative disk disease and lives with severe chronic pain. Unable to receive adequate pain management, she found kratom, uses it in moderate amounts, and it works for her. This Shawn Wenzel and this is her kratom story. Disclaimer: None of the content in this or any episode …

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65. Claudia Merandi, Pain Patient Advocate and Author

Kratom Science Podcast
Kratom Science Podcast
65. Claudia Merandi, Pain Patient Advocate and Author
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Hulu’s final episode of Dopesick aired yesterday. “I cancelled my Hulu account,” says my guest, Claudia Merandi. “I called it Dopesickening. Hollywood had to profit off the pain community… I refuse to watch.” Claudia Merandi has suffered from Chrohn’s disease since she was a child, as documented in her book Crohn’s: The Other ‘C’ Word: …

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Journal Club #14, Q&A Part 1: Kratom and Liver Enzymes, Alcohol, Pain Management, and Serotonin

Journal Club with Dr. Jonathan Cachat
Journal Club with Dr. Jonathan Cachat
Journal Club #14, Q&A Part 1: Kratom and Liver Enzymes, Alcohol, Pain Management, and Serotonin
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Note: Nothing in this podcast or on KratomScience.com is intended to be medical advice, nor should it be taken as such. We’re not medical doctors. Please don’t listen to podcasts for advice on what you should or should not put in your body. For episode #14, Dr. Jonathan Cachat answers half of the remaining question …

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Journal Club #9: Speciofoline, the Understudied Alkaloid

Journal Club with Dr. Jonathan Cachat
Journal Club with Dr. Jonathan Cachat
Journal Club #9: Speciofoline, the Understudied Alkaloid
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A study on kratom’s chemical composition asks, what does the little-researched kratom alkaloid speciofoline do? And what are the implications for drug interactions and the differences in alkaloid content in kratom products? The brand new study published last week in Scientific Reports examined the chemical composition of 53 kratom products and divided them into two …

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Journal Club #8: Kratom Tea for Opioid Dependence in Mice

Journal Club with Dr. Jonathan Cachat
Journal Club with Dr. Jonathan Cachat
Journal Club #8: Kratom Tea for Opioid Dependence in Mice
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This week we look at a study by a team from University of Florida called “Lyophilized Kratom Tea as a Therapeutic Option for Opioid Dependence”. The science is catching up with what thousands of kratom consumers are saying — that kratom can be a safe and effective harm reduction tool for opioid withdrawal and dependence. …

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39. Recovery in the UK with Paul W.

Kratom Science Podcast
Kratom Science Podcast
39. Recovery in the UK with Paul W.
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Paul W was prescribed hydrocodone following a car accident… the beginning of a long journey with opioid pain pills. Living in Florida during the golden age of pill mills (early 2000s) didn’t help. After addiction, recovery, and relapse Paul moved to Italy where he met his future husband. They moved to England where Paul relapsed …

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Journal Club #6: 1972 Animal Study Shows the Promise of Mitragynine

Journal Club with Dr. Jonathan Cachat
Journal Club with Dr. Jonathan Cachat
Journal Club #6: 1972 Animal Study Shows the Promise of Mitragynine
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Citation: Macko E, Weisbach JA, Douglas B. Some observations on the pharmacology of mitragynine. Archives Internationales de Pharmacodynamie et de Therapie. 1972 ;198(1):145-161. We discuss this study from 1972 that tested the effects of mitragynine in rats, mice, cats, dogs, and monkeys. Dr. Jon talks about the difference between now and then in pharmacology labs. …

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Journal Club w/ Dr. Jonathan Cachat #5: Mitragynine Study in Rats Leads to Interesting Conclusions

Journal Club with Dr. Jonathan Cachat
Journal Club with Dr. Jonathan Cachat
Journal Club w/ Dr. Jonathan Cachat #5: Mitragynine Study in Rats Leads to Interesting Conclusions
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Dr. Cachat and I talk about a study that tested rats with morphine, mitragynine, naloxone, buprenorphine, and rimonabant, and measured responses based on food-reinforcement training. The study concluded “The findings suggest that MG does not induce physiological dependence but can alleviate the physical symptoms associated with morphine withdrawal”. We talk about how the rats are …

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33. Pain Management for Interstitial Cystitis with Maranda Flynn

Kratom Science Podcast
Kratom Science Podcast
33. Pain Management for Interstitial Cystitis with Maranda Flynn
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Maranda was diagnosed at 22 with interstitial cystitis, a painful bladder disease. She went into pain management and became addicted to opiates. After 3 years a friend introduced her to kratom. she got out of opiate hell, and was able to be present for her children and husband, who also used kratom to beat alcoholism. …

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